Metabolic

5-Amino-1MQ is not a peptide at all; it is built as a small chemical compound rather than a chain of linked amino acids, and it works by blocking an enzyme called NNMT that cells use during energy processing.

Adipotide is a lab-made compound built from two joined parts: one part latches onto the network of small blood vessels supplying white body fat, while the other part carries a signal that causes those vessel-lining cells to die off.

AOD-9604 is a piece cut from human growth hormone and built in the lab; it uses only the final stretch of the hGH chain with one extra amino acid attached, and it was made to trigger fat breakdown while skipping the wider growth-promoting effects that come with the full-length hormone.

Cagrilintide is a manmade copy of amylin built to last much longer in the body; amylin itself is a natural hormone that plays a role in appetite and in keeping blood sugar steady.

Eloralintide is an experimental, laboratory-made hormone analog developed by a pharmaceutical company as a candidate obesity treatment.

Made of three amino acids joined together, glutathione occurs naturally inside almost all of the body's cells, where it helps guard against chemical damage and is often nicknamed the body's chief antioxidant.

The body assembles L-carnitine on its own out of two amino acids, lysine and methionine.

Scientists built mazdutide in the lab using oxyntomodulin, a hormone the gut makes naturally, as the template, then engineered it to flip on two separate hormone switches together, one tied to GLP-1 and one to glucagon; that dual action is why the field calls it a dual agonist.

MOTS-c is a peptide of just 16 amino acids with an unusual origin: its instructions sit in the DNA inside mitochondria, the parts of the cell that generate energy, rather than in the cell's main nuclear DNA.

Rather than a peptide, orforglipron is a small molecule that activates the same gut hormone receptor targeted by injectable weight and diabetes drugs.

Retatrutide is a lab-made peptide currently moving through late-stage human trials rather than sitting on pharmacy shelves.

GLP-1 is a natural gut hormone, and Semaglutide reproduces it in lab-made form, redesigned so it keeps working in the body for roughly a week rather than fading within minutes.

Made in a lab at Saint Louis University, SLU-PP-332 is a compact molecule built from ordinary chemistry rather than a peptide, designed to switch on a group of cell receptors called estrogen-related receptors.

Survodutide is a lab-made peptide built from 29 amino acids and carrying an attached fat molecule that slows how quickly the body clears it.

Growth hormone-releasing hormone is the body's own instruction to release growth hormone from the pituitary gland, and Tesamorelin is a laboratory-made version of that signal.

Tesofensine is a small manufactured molecule, not a peptide, first studied as a possible treatment for Parkinson's disease and Alzheimer's disease.

Tirzepatide is made in a lab to switch on two different gut-hormone receptors together, GIP and GLP-1, both part of the body's normal system for managing blood sugar and appetite after eating.